Aftercare That Preserves Your Subtle Result: The 24–72 Hour Botox Care Plan
- Avere Beauty Insights Team

- Aug 9
- 8 min read
📌 Key Takeaways:
The first 72 hours after Botox determine whether your results look natural or overdone.
Stay Upright and Hands-Off: Keep your head elevated and avoid touching injection sites for the first 4 hours to ensure even product distribution.
Heat is the Enemy: Skip saunas, hot yoga, and steam rooms for 24-48 hours because heat increases blood flow and can cause product migration.
Time Your Return to Exercise: Light walking is fine after 4 hours, but wait 24-48 hours before resuming vigorous workouts to prevent swelling and pressure effects.
Sleep Smart: Use slight elevation and avoid face-down positions the first night to minimize swelling and protect treated areas.
Know When to Call: Contact your provider immediately for asymmetric drooping, severe pain, vision changes, or spreading redness—these require professional evaluation.
Simple aftercare choices in the first three days preserve the subtle, refreshed look you invested in.
For busy professionals in Pittsburgh and surrounding areas who want to maintain their natural appearance while maximizing their Botox investment.
Reviewed by a licensed clinician (PA-C/NP/MD). Educational guidance only; individual results vary.
The appointment's done. You're walking out feeling good about your decision to refresh your look with Botox injections in Pittsburgh. Now comes the part that actually determines how natural your results will look.
Those first 72 hours aren't just about healing—they're about preserving the subtle, balanced outcome you invested in. The micro-choices you make during this window can mean the difference between that refreshed-but-still-you look and results that feel overdone or uneven.
Here's your complete timeline for protecting your investment and ensuring your Botox settles exactly as intended.
Your First 72 Hours, At a Glance
Print this checklist and keep it handy:
DO | DON'T |
Stay upright several hours after treatment | Rub, press, or massage injection points |
Use gentle cleanse + bland moisturizer | Apply makeup over puncture points on Day 1 |
Take light walks; postpone hard workouts | Hot yoga, sauna, steam for 24–48 hours |
Sleep slightly elevated the first night | Sleep face-down or on tight travel pillows |
Cool (not pressure) compress for minor bruise | NSAIDs or alcohol early on (unless prescribed otherwise) |
For subtle, even results, avoid pressure and heat, keep activity light at first, and keep skin clean and gentle. Stay upright for the early hours, skip saunas and strenuous workouts the first day, and don't rub or press on treated points.
The First 0–4 Hours — "Set It & Forget It"

This is your most critical window. The neuromodulator is still settling into position, and any disruption could affect how evenly it distributes.
Stay upright. Sitting, standing, and ordinary light activity are fine. Avoid lying down, bending over extensively, or putting your head below your heart.
Hands off. No rubbing, pressing, or massaging injection points. This includes resisting the urge to feel for changes or check injection sites.
Makeup pause. Avoid foundation or concealer directly over the tiny puncture marks. Clean brushes and tools are essential if you do apply makeup to other areas of your face.
Remove tight headgear. Skip tight hats, bands, or anything that presses on the forehead or treated areas.
Let your face move naturally. Gentle, natural facial movement is generally acceptable. Smile, frown, and talk as usual—forced "exercise" of muscles isn't necessary.
Why it helps: Minimal pressure and clean skin help protect even diffusion and lower irritation risk. These are widely accepted post-treatment habits across aesthetic clinics.
4–24 Hours — Low-Pressure Only
Think "regular evening at home," not "hot studio class." You can start to relax a bit, but this is still a delicate time for the product to work its way into the right muscle fibers.
Activity: Light walking is fine; postpone vigorous workouts. Easy stretching or gentle yoga poses are acceptable, but avoid anything that gets your heart rate significantly elevated.
Heat and steam: Avoid sauna, steam rooms, and hot yoga. Even very hot showers should be limited. Heat can increase blood flow to your face and potentially cause the product to migrate.
Skin: Gentle cleanse; bland moisturizer. Avoid strong actives right on puncture points. Skip retinoids, alpha hydroxy acids, or any active ingredients directly on or near injection sites.
Makeup: If needed, keep it off the tiny marks; use clean tools and brushes elsewhere.
Alcohol: Best avoided the first night, as it can worsen bruising for some people and increase swelling.
Sleep: Slight elevation helps; try to keep pressure off the face, especially the first night. Consider using a travel pillow to avoid pressing your face into the pillow if you're a side sleeper.
24–48 Hours — Ease Back In

The goal here is steady, not speedy. The product is becoming more stable, but you're still in the integration phase where gentle care makes a difference.
Resume most normal activities, but continue to avoid deep facial massage, gua sha, or rollers. Light exercise like walking or easy cycling can restart.
Heat exposure: Still cautious with steam rooms and prolonged high heat. Moderate temperatures are generally acceptable.
Skincare: You can usually reintroduce routine products; keep strong actives away from puncture points until they look and feel normal.
Monitor for normal healing. Slight swelling, minor bruising, or small bumps at injection sites are completely normal and typically resolve within a few days.
These steps are consistent with common aftercare guidance designed to reduce swelling and protect placement.
48–72 Hours — Stabilize
Most people feel fully "back to normal" here. You're entering the home stretch where the neuromodulator has largely integrated into your muscle tissue.
Exercise: Moderate workouts can usually resume if there's no tenderness or swelling. Start with moderate intensity and see how you feel.
Skincare: Return to your standard routine as tolerated, including active ingredients, as long as your skin tolerates them well.
Rule to keep: Avoid direct, deep pressure on treated areas for roughly a week. Even though the product is more stable, direct pressure or manipulation can still affect your results.
Results are starting to show. You might begin noticing the subtle smoothing effects, though full results typically develop over 1-2 weeks.
Can I…? Fast Answers
Exercise? Light walking after about 4 hours is typically fine. Many providers recommend waiting roughly 48 hours for vigorous training to reduce swelling or pressure effects.
Sauna/steam/hot yoga? Best avoided for 24–48 hours. High heat and heavy sweating can aggravate swelling or irritation.
Makeup? Skip makeup on the small puncture points the first day. After that, apply with clean tools to lower the risk of irritation.
Facials, massage, rollers? Avoid for 48–72 hours. No deep facial pressure for roughly one week to avoid shifting pressure over treated sites.
Sleep on my side? If possible, avoid heavy facial pressure the first night. A slightly elevated position can help minimize swelling.
Fly after treatment? Generally acceptable. Avoid face-down travel pillows that press on treated areas.
Bruising or swelling? Mild swelling or a small bruise can happen. A cool (not pressure) compress can be soothing. Avoid blood thinners and NSAIDs unless they were prescribed for another reason.
Headache? Mild headache can occur and usually resolves quickly. Acetaminophen is commonly used; avoid NSAIDs unless prescribed. If pain is severe or unusual, contact your provider.
Notes above reflect widely observed, conservative practices. Your own provider's instructions take precedence.
When to Call Your Provider
While serious complications are rare, certain symptoms warrant immediate attention. Seek timely care if you notice any of the following:
Call immediately if you experience:
Asymmetric droop or pronounced unevenness that wasn't present before
Severe pain, significant swelling that worsens, or fever/spreading redness
Visual changes, new numbness, or anything that feels alarming or unusual
Signs of allergic reaction
Pittsburgh location: 412-952-7592
Export/Murraysville location: 724-575-7884
Patients of Avere Beauty can call the office directly for guidance. If urgent, seek immediate medical attention. Most side effects are mild and temporary, but your provider should always be your first resource for concerns about your specific situation.
Local Notes for Pittsburgh & Export/Murraysville
Schedules get busy around fall resets and holiday events. The plan above emphasizes low downtime and minimal effort, which aligns well with tight calendars and changing weather in Western Pennsylvania. If you're moving between downtown meetings and evening workouts, use the 24–48 hour window as your buffer before returning to high-heat classes or heavy training.
Make Results Last (Look Like You)
A few long-game habits help preserve soft, authentic results between appointments:
Daily SPF. Sun protection supports even skin tone and complements a refreshed look. Consistent sun protection remains your most important anti-aging strategy.
Steady skincare. Consistent, gentle routines tend to outperform sporadic experimentation. The team at Avere Beauty can recommend medical-grade options that complement your treatment results.
Professional follow-ups. Plan your cadence with your injector; modest, regular touch-ups often look more natural than large, infrequent jumps. Most people see optimal results with treatments every 3-4 months.
Loyalty programs. Savings platforms like Allé can help you maintain a consistent schedule without rushing decisions, encouraging the consistent care that produces the best long-term outcomes.
Lifestyle basics. Hydration, sleep, and stress management may not be glamorous but often show up on your skin.
For personalized planning, start with Botox injections in Pittsburgh. If you're also researching volume restoration, see our overview of dermal fillers (separate treatment; not an aftercare step).
Book Your Professional Follow-Up
Your aftercare doesn't end when the initial healing is complete. A follow-up appointment allows your provider to assess your results and make any minor adjustments if needed.
Ready to schedule your next visit or have questions about your current results? The experienced team at Avere Beauty is here to support your aesthetic journey with the same attention to detail that made your initial treatment successful.
Get started easily:
Email for pricing information
Call our Pittsburgh office at 412-952-7592
Call our Export/Murraysville office at 724-575-7884
Visit us in person:
Pittsburgh: 3453 Butler Street, Pittsburgh, PA 15201
Export/Murraysville: 5100 Old William Penn Hwy, Export, PA 15632
Frequently Asked Questions
How long until results are visible?
Early changes can appear within a few days, with most improvement developing over 1–2 weeks. Timing varies by area, dose, and individual factors. Your provider will set expectations for your specific plan.
Can I take a shower the same day?
Yes—use lukewarm water and avoid direct, hot steam on the face that first day. Pat dry; don't rub the injection points.
What skincare should I avoid?
Strong acids, scrubs, and vigorous tools can wait until puncture marks look and feel normal. Gentle cleanse and moisturizer remain the baseline.
Is bruising normal?
A small, localized bruise can happen with any injection. It usually fades on its own. A cool, light (no pressure) compress can be soothing. Contact your provider if bruising is extensive or accompanied by concerning symptoms.
When should I schedule my next visit?
Your injector will recommend a cadence based on goals and treatment area. Many patients prefer a proactive check-in to fine-tune results, rather than waiting for a full fade.
Important safety note: This guide is educational and not a diagnosis or treatment plan. It reflects commonly accepted aftercare practices for neuromodulator injections. Always follow your own provider's instructions. Individual results vary.
Where to next?
Learn service details on Botox injections in Pittsburgh
New to in-office treatments? Read What to Expect
Exploring broader options? Our Med Spa hub covers additional services (for example, laser hair removal)
About Avere Beauty
Avere Beauty is Pittsburgh's premier medical spa, specializing in natural-looking aesthetic treatments. Our experienced team of nurses and medical professionals believes in enhancing your natural beauty through careful, conservative treatment approaches. Located in both Pittsburgh's Lawrenceville neighborhood and Export/Murraysville, we're committed to providing exceptional care and results that help you look and feel your best.







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